12024-07-17T23:49:32+00:00Ivan Portillo741ad6f42573dbb784db9511d4627772eb86aa1936731717: Lady Mary Wortley Montagu, the wife of the British ambassador to the Ottoman Empire, observed variolation and was impressed by its effectiveness. She wrote letters to her friends in Europe, advocating for its adoption, which led to greater awareness and interest in the practice. Image Attribution: Samuel Freeman, Public domain, via Wikimedia Commonsplain2024-07-19T16:43:35+00:001717Ivan Portillo741ad6f42573dbb784db9511d4627772eb86aa19